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Research Movies

Video

Long-term imaging of cancer cell proliferation.

Long-term imaging of diploid cells expressing the FUCCI system. Red cell are in G1, green cells are in S/G2/M. Ganem et al, 2014, Cell

Long-term imaging of tetraploid cells expressing the FUCCI system. Tetraploid cells arrest in G1 phase. Ganem et al, 2014, Cell

Long-term imaging of tetraploid cells expressing the FUCCI system. Tetraploid cells  depleted of p53 are Abel to overcome G1-arrest. Ganem et al, 2014, Cell

Generate excitement

Extra centrosomes promote chromosome mis-segregation by forcing cells through a transient multipolar spindle intermediate during which time merotelic kinetochore attachments accumulate. Ganem et al, 2009, Nature